Table 1 Active ingredients in each class of anticancer drugs and the factors used in the conversion
Drug class | Active ingredients | Conversion factor |
|---|---|---|
Inosine monophosphate dehydrogenase inhibitor | - Mycophenolic acid (MPA) - Mycophenolate mofetil (MMF) | 1440 mg MPA = 2000 mg MMF [8] |
Antimetabolites | - Capecitabine - 5-Fluorouracil | 2.76  mg CAP = 1 mg 5-Fluorouracil [9] |
Alkylating agents | - Cyclophosphamide - Ifosfamide | 1 mg cyclophosphamide = 0.244 ifosfamide [10] |
Anthracyclins | - Epirubicin HCl - Mitoxantrone - Doxorubicin - Idarubicin HCl | 75 mg Epirubicin = 12.50 mg Mitoxantrone = 50 mg Doxorubicin = 10 mg idarubicin [11] |
Taxanes | - Docetaxel - Paclitaxel | 135 mg Paclitaxel = 75 mg Docetaxel |
Antimetabolites | - Methotrexate - Pemetrexed | 1.50 mg Methotrexate = 150 mg Pemetrexed [12] |
LHRH agonist: Goserelin equivalent | - Goserelin - Leuprorelin - Triptorelin | 3.60 mg Goserelin = 7.50 mg Leuprorelin = 3.75 mg Triptorelin [13] |